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Onpattro (patisiran) is a medication used for the treatment of hereditary transthyretin-mediated amyloidosis (hATTR) in adults. Here’s information about its uses, benefits, common symptoms, and potential side effects: Onpattro Tablet Uses Benefits and Symptoms Side Effects

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Onpattro Tablet Uses Benefits and Symptoms Side Effects

 

 

Onpattro Tablet Uses Benefits and Symptoms Side Effects

 

 

Uses and Benefits of Onpattro (Patisiran):

  1. Hereditary Transthyretin-Mediated Amyloidosis (hATTR): Onpattro is indicated for the treatment of hATTR, a rare genetic disease characterized by the buildup of abnormal protein (amyloid) in various organs, leading to organ damage and dysfunction. Onpattro works by interfering with the production of the abnormal protein, thereby slowing the progression of the disease.

Common Symptoms and Side Effects of Onpattro (Patisiran):

  1. Infusion-Related Reactions: Onpattro is administered intravenously, and infusion-related reactions can occur during or shortly after the infusion. Symptoms may include fever, chills, flushing, shortness of breath, dizziness, nausea, or headache. These reactions are usually mild to moderate in severity and can be managed with medications.
  2. Peripheral Edema: Some individuals may experience peripheral edema, which is swelling in the hands, feet, or ankles.
  3. Gastrointestinal Symptoms: Common gastrointestinal symptoms associated with Onpattro include diarrhea, abdominal pain, and nausea.
  4. Upper Respiratory Tract Infections: Onpattro can increase the risk of upper respiratory tract infections, such as the common cold or flu.
  5. Kidney Dysfunction: In some cases, Onpattro may cause kidney dysfunction, leading to changes in kidney function tests or the need for dialysis.
  6. Hypersensitivity Reactions: Rarely, Onpattro can cause hypersensitivity reactions, including rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.

It’s important to receive

Onpattro under the supervision of a healthcare professional who is experienced in the administration of intravenous infusions. The dosage and infusion schedule will be determined by your healthcare provider based on your specific condition and response to treatment.

Inform your healthcare

provider about any pre-existing medical conditions, medications, or supplements you are taking to ensure the appropriate use of Onpattro.

If you have any concerns or experience

troubling side effects while receiving Onpattro, consult with your healthcare provider for further evaluation and guidance. They can provide personalized advice based on your specific situation and help you manage your hATTR effectively.

 

 

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